This chapter looks at mobile business (MoB) from technological, social, economical, and environmental perspectives. The issues that surround MoB and hence, influence its success at the wider scale in the long run, are dependent on significant factors addressed in this chapter. The chapter defines MoB and looks at different mobile technologies and standards that enable MoB. The chapter then looks at the different factors and contexts that would influence MoB success at a broader level, highlighting issues, gaps, and challenges. It is emphasised that unless such implications are addressed, the wide diffusion of MoB will not materialise in the near future. Despite the rapid technological development and the enthusiasm about the MoB innovation among researchers and professionals, the road toward true MoB is still a long one. What exist now in the market are just complementary solutions. At this level, at the lower end, MoB is the toy of the teenagers; at the higher end it is the toy of the rich or the executive who cannot tolerate to be away from his/her e-mail. There are indeed some useful business applications for MoB, especially in logistics and distribution, but the remaining potential masses that have tasted the beauty of Internet browsing are not yet prepared to compromise that with ill-specified mobile technologies, e.g., devices, wireless communications, and deficient and stripped down contents. Still, MoB stands strong as a futuristic direction and one day we will be there, wearing MoB.