The question raised in this chapter, “What can cave walls teach us?” is essential because education is increasingly taught within a ubiquitous global electronic venue. Since much of the current electronic learning (e-learning) education environment has been produced in the United States of America, Canada, and Western Europe, many other countries, such as China, Japan, India, and Africa are currently left out of e-learning designs. So the question of how to provide e-learning that accommodates the diverse learning needs of multicultural and multinational learners is becoming critical. This chapter discusses some of the ways instructional designers and educators can utilize lessons learned from the past to facilitate a renaissance of learning across cultures and nations and incorporate prior learning legacies into facilitative, 21st century e-learning. Positive by-products will include more equitable learning opportunities for targeted learners through e-learning and, optimally, more well-rounded learners.