This chapter asks “What is meant by computermediated communication research?” Numerous databases were examined concerning business, education, psychology, sociology, and social sciences from 1966 through 2005. A survey of the literature produced close to two thousand scholarly journal articles, and bibliometric techniques were used to establish core areas. Specifically, journals, authors, and concepts were identified. Then, more prevalent features within the dataset were targeted, and a fine-grained analysis was conducted on research-affiliated terms and concepts clustering around those terms. What was found was an area of scholarly communication, heavily popularized in education-related journals. Likewise, topics under investigation tended to be education and Internet affiliated. The distribution of first authors was overwhelming populated by one time authorship. The most prominent research methodology emerging was case studies. Other specific research methodologies tended to be textually related, such as content and discourse analysis. This study was significant for two reasons. First, it documented CMC’s literature historical emergence through a longitudinal analysis. Second, it identified descriptive boundaries concerning authors, journals, and concepts that were prevalent in the literature.