Advancements in information technology have transformed much in all aspects of today’s society. In particular, synchronous and asynchronous electronic communication systems support countless interactions every day. However, these communication systems have specific limitations that can cause miscommunications as well. Because of that, computer-mediated communications (CMC) has been a robust research agenda in many disciplines. This is especially true of education, where online learning has become common place in all but a few universities, thus requiring learners to interact via CMC within virtual learning environments. This chapter will use educational CMC research as a lens to promote and support an understanding of how to better utilize and facilitate electronic communication, regardless of the field or endeavor.