This exploratory study examined the effects of cross-cultural learning dimensions on e-learning outcomes for employees in functionally equivalent jobs in Western and Eastern cultures. Participants from the United States and India completed a Level 1 e-learning course designed in the United States. In addition, randomly selected completers then reported their interactions with the e-learning course in a survey. Learners from the two cultures achieved equitable learning outcomes, suggesting that characteristics of Level 1 e-learning courses mediate the effects of culture. In addition, while cross-cultural dimensions did appear to affect learners’ preferences for and perceptions of e-learning, both Eastern and Western participants were willing to try new approaches to learning that did not align with their cultural profiles. Based on these results, the cultural adaptation process (CAP) model is presented as a preliminary guideline for adapting e-learning courses for other cultures. Accelerated dissemination of Level 1 courses could increase technological literacy . Education and technological innovation are strongly associated with advanced socio-economic development.