The encouragement of learner-to-learner interaction in asynchronous discussions can be achieved by providing learner support in the early stages of course delivery. This not only smoothes the transition to e-learning but also contributes to knowledge construction and enhancement of learning outcomes. In this chapter, the author describes improvements to orientation activities that enabled learners to work collaboratively in online groups. The activities are closely aligned with Salmon’s five-stage model and illustrate the dynamics of online learning in groups. Research conducted by the author examining the effectiveness of the orientation activities has lead to identification of key issues and practical suggestions that will assist the readers of the chapter to develop approaches to learner support in their own context.