This chapter introduces the importance of the Information and Communication Technologies on the regional development in Turkey. Socioeconomic transformation can be done with the efficient service opportunities in regions that have different growth rates. Specially, some regions have migration problems for economic and employment reasons in Turkey. Growth poles are a typical development style for Turkey. Therefore, less developed regions should have more advantage from national economic programs. In this chapter, included in Regional development programs of Turkey in the context of Information and Communication Technologies. The objective of this chapter is to point out importance of improvements of Information and Communication Technologies and e-government programs in Turkey. At this time, it is defined the role of e-government programs on social, economic and political structures of the regions in Turkey.