This case aims to analyze, in some detail, the major challenges in the widespread adoption of electronic commerce in the Spanish-speaking population. The case also provides a general overview of related issues in global e-commerce, specifically: language, localization, currency, cultural difference, export controls, payment methods, taxation issues, consumer protection, and legal issues. The case includes a description of the strategies followed by companies entering the Latin American market in order to illustrate some of the major cross-border issues. The case clearly exemplifies how localization involves a considerable financial investment and commitment. The chapter illustrates that while Latin America initially attracted many investors by offering one of the world’s fastest growing online populations, the market was not large enough to accommodate all the new entrants.