RFID-enabled business models are proposed in this chapter to innovate supply chain management. The models demonstrated benefits from automatically captured real-time information in supply chain operations. The resulting visibility creates chances to operate businesses in more responsive, dynamic, and efficient scenarios. The actual initiative of such novel RFID enabled applications is therefore to encourage intelligent supply chain management to dynamically respond changes and events in real-time. As the RFID implementation costs are continuously decreasing, it is expected that more novel business models would be inspired by the technological advancement to foster more intelligent supply chains in the near future.