This chapter explores how Mixed Reality (MR) allows the magic of virtuality to escape the confines of the computer and enter our lives to potentially change the way we play, work, train, learn and even shop. Case studies demonstrate how emerging functional capabilities will depend upon new artistic conventions to spark the imagination, enhance human experience and lead to subsequent commercial success. The Media Convergence Laboratory at the University of Central Florida is creating a content framework for applying Mixed Reality to Entertainment, Education Training and Rehabilitation. Utilizing classical concepts of mimesis and state-of-the-art experiential entertainment, new models are examined and evaluated that will shape the next generation MR content. The convergence of story, play and games become the cornerstones of “Interplay Conventions” that will transform MR technical capabilities into new creative possibilities (“The Evolution of a Framework for Mixed Reality Experiences” is the technical companion piece).