The fall of the Berlin Wall, the collapse of the Warsaw Pact, and the disintegration of the Soviet Union are certainly monumental events in the history of the human race as the 20th century nears its close. Monumental changes are taking place in business organizations and in the managers who run them. The business community is shifting its paradigms and the manner in which it does business. To avoid “Future Shock,” one must look beyond the trends of the past and discover the rules that will govern business in the Twenty-First Century, the Information Age. By knowing the nature of such changes and how to anticipate them, the strategist can elicit extraordinary leverage in shaping the future. Drucker (1980) in Managing Turbulent Times, writes that one of the most important skills during times of turbulence is anticipation. This chapter explores the effects of the information age (Figure 1) upon the global business enterprise which is shifting from an old paradigm to a new one, in the way Kuhn (1970) described paradigm shifts in science in The Structure of Scientific Revolutions. We will also suggest that since all major business dimensions have shifted paradigms, a new era in business requires a new set of rules.