This chapter introduces e-procurement as a strategic tool for organizations’ competitive position in the new information economy. It argues that that eprocurement is significantly changing the ways businesses operate and thus new business models are needed. E-procurement success factors that have to be considered are: cost factors, time factors, process simplification factors and the volume of e-transactions factors. By gaining understanding of the most important e-procurement factors, organizations have to organize themselves in a way that ensures success. Furthermore, author hopes that with knowing such factors, organizations will be able to better prepare for e-procurement and thus operate successfully and thus be able to compete in the global market.