This chapter presents the strategies of higher education institutions and how they can be described using the balanced scorecard approach. The pedagogical ICT strategy describes the virtual learning and e-entrepreneurship in higher education. Strategic themes are presented to describe what management believes must be done to succeed and achieve the desired outcomes in virtual learning and e-entrepreneurship. Strategy maps are used to describe the strategy in a graphical representation. In addition, the study presents an example of the cooperation between a higher education institution and a spin-off company. This chapter helps the educational administrators to better describe and implement strategies for virtual learning and e-entrepreneurship.