As information communication and technologies (ICT-) enabled services such as e-government initiatives diffuse globally, it is becoming clear that some nations are not faring as well as others. Yet, the notion of e-government stands to benefit the sorts of countries that are lagging behind the most. Here, we examine the relationships between economic climates and national cultural factors, on the one hand, and e-government readiness, on the other. Our results showed significant relationships between nations’ economic climates, some cultural dimensions, and e-government readiness. We discussed our findings in the context of three relevant socio-economic theories. We also highlighted the study’s implications for researchers, policy-makers, and governments.