Class of clustering algorithms that perform clustering on the rows and columns of a data matrix at the same time. It is also known as co-clustering, two-dimensional clustering, or two-way clustering.
Published in Chapter:
Biclustering of DNA Microarray Data: Theory, Evaluation, and Applications
Alain B. Tchagang (National Research Council, Canada), Youlian Pan (National Research Council, Canada), Fazel Famili (National Research Council, Canada), Ahmed H. Tewfik (University of Minnesota, USA), and Panayiotis V. Benos (University of Pittsburgh, USA)
Copyright: © 2011
|Pages: 39
DOI: 10.4018/978-1-60960-491-2.ch007
Abstract
In this chapter, different methods and applications of biclustering algorithms to DNA microarray data analysis that have been developed in recent years are discussed and compared. Identification of biological significant clusters of genes from microarray experimental data is a very daunting task that emerged, especially with the development of high throughput technologies. Various computational and evaluation methods based on diverse principles were introduced to identify new similarities among genes. Mathematical aspects of the models are highlighted, and applications to solve biological problems are discussed.