Quality Control of Cellular Protein in Neurodegenerative Disorders
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Quality Control of Cellular Protein in Neurodegenerative Disorders

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Release Date: February, 2020|Copyright: © 2020 |Pages: 515
DOI: 10.4018/978-1-7998-1317-0
ISBN13: 9781799813170|ISBN10: 1799813177|EISBN13: 9781799813187
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Description & Coverage
Description:

Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration.

Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.

Coverage:

The many academic areas covered in this publication include, but are not limited to:

  • Alzheimer’s Disease
  • Autophagic Dysfunction
  • Cellular Cysteine Network
  • Huntington's Disease
  • Molecular Chaperones
  • Parkinson’s Disease
  • Post-Translational Modifications
  • Proteasome Dysfunction
  • Protein Misfolding
  • Stress Signaling
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Editor/Author Biographies

Md. Sahab Uddin is a Registered Pharmacist and a Research Scholar in the Department of Pharmacy at Southeast University, Dhaka, Bangladesh. He has published copious articles in peer-reviewed international scientific journals. He has also authored and edited seven books, including Advances in Neuropharmacology: Drugs and Therapeutics; Handbook of Research on Critical Examinations of Neurodegenerative Disorders; and Oxidative Stress and Antioxidant Defense: Biomedical Value in Health and Diseases. Md. Uddin also serves as a guest editor, editorial and reviewer board member of numerous scholarly journals. He is a member of many national and international scientific societies. He has developed five neuropsychological tests for the estimation of memory, attention, and cognition. Moreover, he is the Founder and Executive Director of the Pharmakon Neuroscience Research Network, an open innovation hub bringing together neuroscientists to advance brain health. He received his BPharm in 2014 securing a first position from the Department of Pharmacy, Southeast University, Bangladesh. Md. Uddin’s research interest is how neuronal operation can be restored to abate Alzheimer’s dementia.

Ghulam Md. Ashraf is currently working as an Associate Professor at King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. Md Ashraf received his PhD in Biochemistry from Aligarh Muslim University, India in 2010. He has to his credit 191 publications ranging from peer-reviewed journal articles, books and book chapters published with the scholarly publishers (total citations: 2473, h-index: 22, i10-index: 68). He has been involved in 13 research projects funded by various agencies of Saudi Arabia and is a member of several renowned professional associations and organizations. Md Ashraf currently focuses on investigating the expression of proteins involved in causation, progression and potential therapy of neurological disorders. He is also interested in exploring the inherent connection of neurological disorders with other chronic diseases. Md Ashraf is involved in the editorial capacity in many reputed journals, like PLOS one, Scientific Reports, Frontiers in Neuroscience, Current Proteins and Peptides, Journal of Proteomics, to mention a few. Dr. Ghulam Md Ashraf received his PhD in Biochemistry from Aligarh Muslim University in 2010. Dr. Ashraf is currently working as Associate Professor at King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. His current research interest covers proteomics, neurology, nanotechnology and cancer. Dr. Ashraf has published 160 research articles in books and journals of international repute. Dr. Ashraf is involved in editorial capacity in many internationally reputed journals, and have been involved in 6 research projects funded by various agencies of Saudi Arabia. View Ghulam Md. Ashraf's Researchgate profile here. View Ghulam Md. Ashraf's Google scholar profile here.
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