Data Mining and Machine Learning Approaches in Breast Cancer Biomedical Research

Data Mining and Machine Learning Approaches in Breast Cancer Biomedical Research

Gunavathi Chellamuthu, Kannimuthu S., Premalatha K.
DOI: 10.4018/978-1-5225-4999-4.ch011
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Abstract

Breast cancer is the most common invasive cancer in females worldwide. Breast cancer diagnosis and breast cancer prognosis are the two important challenges for the researchers in the medical field and also for the practitioners. If the cells in the breast start to grow without any control, it leads to cancer. Normally, the growth of the lump can be seen using x-ray. The benign and malignant breast lumps are distinguished during breast cancer diagnosis. The prognosis process predicts the period at which the breast cancer is likely to reappear in patients who have had their cancers removed. Data mining techniques and machine learning algorithms are mostly used in the whole process of breast cancer diagnosis and treatment. They utilize the large volume of breast cancer data for extracting knowledge. The application of data mining and machine learning methods in biomedical research is presently vital and crucial in efforts to transform intelligently all available data into valuable knowledge.
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Background

In human body, if the cells in the breast are started to grow without any control, it leads to cancer. Normally, the growth of the lump can be seen using x-ray. The affected cells can propagate into nearby tissues or blowout all over the body. More than 100 types of cancer are identified in the medical field and it became one of the major roots of death in the world. There are many factors that influence the formation and spreading of cancers which are listed below:

  • 1.

    Genetics

  • 2.

    Gender

  • 3.

    Age

  • 4.

    Life style

  • 5.

    Environment

  • 6.

    Marital status

Breast cancer is the deadliest disease which is a malevolent cell development in the breast. The cancer cells extend to other parts of the body, if the patient left untreated. The occurrence of breast cancer upsurges after 40 years of age. The incidence of this disease is even high with women over age 50. Breast cancer causes deaths in women which has the second place among other diseases. According to the survey, mortality rates dropped significantly during 1992-1998 with the major decreases in younger women. Breast cancer is most prevalent in women which affect over 13% of all women in the world. There is more number of younger women vulnerable to breast cancer in most of the nations (Richie & Swanson, 2003).

Breast cancer is of two types. They are:

  • 1.

    Harmless breast lump (non-cancerous): The texture and the size of tumor are easy to understand through the basic examination;

  • 2.

    Malignant breast lump (cancerous): Diagnosis of clinical studies needed for predicting this kind of cancer. This type can be further categorized into:

    • a.

      Non-invasive: Affected cells have not extended in other cells and tissues;

    • b.

      Invasive: Affected cells have extended into the neighboring cells and tissues.

Key Terms in this Chapter

Classification: It is a data mining function that assigns items in a collection to target categories or classes.

Machine Learning: It is a field of statistics and computer science that gives computer systems the ability to “learn” with data, without being explicitly programmed.

Data Mining: It is the process of discovering patterns in large data sets involving methods at the intersection of machine learning, statistics, and database systems.

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