Efficacy of Herbal Medicine in Treating Metabolic and Endocrine Disorders

Efficacy of Herbal Medicine in Treating Metabolic and Endocrine Disorders

Chittipolu Ajaykumar
Copyright: © 2021 |Pages: 20
DOI: 10.4018/978-1-7998-4808-0.ch010
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Abstract

Metabolic syndrome is an interrelated cluster of pathogens such as obesity, impaired glucose tolerance, cancer, and insulin resistance leading to endocrinal disorders. In the 21st century, progression of the disease is rapid increases due to change in the lifestyle of humans having a chance to develop metabolic change, and in some cases, mutations occur, which drastically affects the endocrine functionality and subsequently causes syndrome X. In modern medicine, different medications are available but only to maintain the condition lifetime. For the complete cure, WHO focused on the traditional knowledge in 2004, using the herbal medicine to cure all metabolic aliments. According to ancient medical treatment, metabolic syndromes are completely curable. They divided the disease progression stages and formulated the different dosage forms. All the data obtained from the ancient herbal medicine treatment are not evidence-based. So, the researchers all around the world focused on the evidence-based proofs to confirm whether herbal medicine shows efficacy in curing the metabolic syndrome or not.
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Introduction

Since ancient times, human and other animal societies have always depended on plants and their products as a portion of food for survival and curing ailments. Around 3300BC Indigenous groups of people developed knowledge about ethnomedicinal plant-based products through their skills to solve various problems and pandemic situations by practical experiences (Petrovska, 2012). At 3000BC Ayurveda showed up as a treatment for curing aliments and prevent diseases. Later Egyptian medicine, Chinese medicine, and Tibetian traditional treatments used plants as a source of medicines.

Experience-based practices typically are intended to prevent or cure specific diseases or symptoms in a comprehensive fashion, the ancient people have no scientific knowledge of diseases and treatments. The treatments were conducted based on the opportunities had around them. At some point increase the demand for scientific knowledge with the advancements of technology to believe that actually, the herbal medicine is beneficial (Schulz, et, al,2001).

In the 19th-century increase demand for allopathic medicine (modern medicine) because relying on the evidence of effectiveness when considering other medical treatments, with the advancement in industrial techniques both Europe and North America during the early 19th century the production of this medicines increased (Petrovska, 2012).

Allopathic medicinal system approach focuses on the specific region in the human body and exerts pharmacological properties to cure the particular aliments unlike, other techniques ancient technology failed to focus on the preventive measures of treatment. Even though the allopathic medicines are created based on the practical knowledge, almost 40% of the new drugs approved in North America from 1983 to 1994, were derived from herbal plants, and approximately 70% of the new chemical moieties reported between 1981 - 2006 (Newman and Cragg, 2007).

The increase in interest originated in the late quarter of the 20th century, researchers found out that synthetic agents come from technical advancements also have potential side effects alongside benefits. In the case of ayurvedic and other herbal medicine treatment, no side effects were reported, led the researchers towards herbal medicines in the treatment of many diseases (Sen, S., et.al, 2011) (Gurib-Fakim, A.2006). It is important to recognize the plant constituents which are still used today becoming the basis for many synthetic drugs. Due to these findings, researches focus has been shifted to herbal medicine in the treatment of many diseases.

The world health organization has attentive on the traditional knowledge associated with herbal medicine from the early 20th century about 80% of the world population had experience with plant-based medicine for curing primary health. Issues were raised at the same time on the effects of the allopathic medicine increase the possibilities for the developing new bioactive compounds to offer better safety and efficacy (Fokunang, C. N, 2011). The global market for herbal medicine and medicinal plants is estimated to be worth US$800 billion annually. Traditional medicines are continuously increasing due to features like safety and efficacy against diseases (Sheng-Ji, P.2001) (Odugbemi, T. (Ed.). (2008). In today's world, important to recognize a majority of clinical research on in 21st century is based on the herbal entities in addition to a tool of alternative medicine focusing on the efficacy and safety to standardize biomass and manufacturing processes. A recent survey shows the majority of clinical research on herbal medicines in the 21st century involves modernization and globalization, focusing on efficacy and safety (Jachak and Saklani, 2007).

Key Terms in this Chapter

Thyroidism: Imbalance in the production of thyroid hormone from the thyroid gland.

Glucose Intolerance: Metabolic conditions result in higher blood glucose than normal blood glucose levels.

Obesity: Excess body fat has accumulated in the body to the extent that it may harm health. According to WHO, when body mass index (BMI) higher than 30% then considered as obesity.

Insulin Resistance: Inability caused in fat, muscles, and liver don't respond well to insulin thereby glucose in the blood failed to use for energy production.

Metabolic Syndrome: The disorders at metabolic state in the organism caused by genes and other lifestyle issues.

Cancer: Growth of abnormal cells in the body from uncontrolled cell division.

Herbal Medicine: Describes as an alternative and pseudoscientific medicine used for promoting health by using unpurified plant extracts.

Pharmacovigilance: A science relating to the collection, detection, assessment, monitoring, and prevention of adverse effects through pharmaceutical products.

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