Insulin DNA Sequence Classification Using Levy Flight Bat With Back Propagation Algorithm

Insulin DNA Sequence Classification Using Levy Flight Bat With Back Propagation Algorithm

Siyab Khan, Abdullah Khan, Rehan Ullah, Maria Ali, Rahat Ullah
DOI: 10.4018/979-8-3693-3026-5.ch043
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Abstract

Various nature-inspired algorithms are used for optimization problems. Recently, one of the nature-inspired algorithms became famous because of its optimality. In order to solve the problem of low accuracy, famous computational methods like machine learning used levy flight Bat algorithm for the problematic classification of an insulin DNA sequence of a healthy human, one variant of the insulin DNA sequence is used. The DNA sequence is collected from NCBI. Preprocessing alignment is performed in order to obtain the finest optimal DNA sequence with a greater number of matches between base pairs of DNA sequences. Further, binaries of the DNA sequence are made for the aim of machine readability. Six hybrid algorithms are used for the classification to check the performance of these proposed hybrid models. The performance of the proposed models is compared with the other algorithms like BatANN, BatBP, BatGDANN, and BatGDBP in term of MSE and accuracy. From the simulations results it is shown that the proposed LFBatANN and LFBatBP algorithms perform better compared to other hybrid models.
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2. Background

There are numerous categories which are used for the problem of classifications in which of them the first one model based, similar to the Markov model (HMM), sequence-sequence classification and further statistical models like linear regression, logistic regression etc. Used for the classification of the biological sequences like DNA, protein and RNA, etc. in the past. In the mentioned models the biological sequences are classified on the origin of the highest alignment score. The only alignment score is not there, also some additional parameters to check for the improved classification (Xing, Pei, and Keogh, 2010).

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