Machine Learning Is the Future for Lung Cancer Prognosis and Prediction

Machine Learning Is the Future for Lung Cancer Prognosis and Prediction

Ayshwarya Balakumar (Kristu Jayanti College, India) and Senthil S. (REVA University, India)
DOI: 10.4018/978-1-7998-2101-4.ch011
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Abstract

Lung cancer is one of the major reasons for the death if it is not diagnosed in the early stages of cancer. It is the one among the most dreadful disease which affects in the lungs function. It can be identified only after the disease spread into the deeper parts of the lungs and then only it will make a life threading problem. Lung cancer prognosis which was done based on the various parameters such as age, sex, condition of smoking, duration of smoking and count of smoking per day. The proceedings were done using the algorithm for the time to first cigarette after awakening which is represented as TTFC. The expert doctor says that the back-propagation network is a great deal in the recognition of the lung cancer without any involvement by them. This research is based on the classification of lung cancer and its stages using the establishment of the BPN and predicts the recurrence. Similarly, with this BPN, an algorithm that is inspired from its habitat known as ant lion optimization algorithm is also used in the optimization of weights and parameters of the BPN. The use of the ALO algorithm provides an improved convergence mechanism by improving the proposed technique's accuracy. The use of this proposed method with the BPN optimizes the network and the ALO optimizer provides an accurate prediction of the lung cancer by the earlier stage and even predicts the changes for reoccurrence after diagnosis. The prognosis analysis was made by the various comparative study between the characteristic features of HIV and the unaffected person using the algorithm such as the Wilcoxon rank-sum test. This algorithm will continuously classify the viral load and CD4 count which is based on factors such as age, sex, and smoking activities. It will be useful for early diagnosis and future prediction. Lung cancer rates can be analyzed based on the incident rates of affected and unaffected persons to HIV infections.
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Introduction

The unrestricted development of cells in the lung tissues causes the lung cancer which is termed as lung carcinoma. Lung carcinoma is a malicious lung cancer. The growth would spread outside the lung which process is termed as metastasis to the adjacent tissues and the other parts of the body. The classification of lung cancer is as follows: Non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). The performance is segregated depending on the observation of the equipment of tumor cells using the microscope. These divisions of cancer are handled, developed, and dispersed by various methods. The major reason for lung cancer is cigarette smoking which would include various diseases such as peripheral arterial disease and coronary artery disease. Cigarette smoking may lead to atherosclerosis which would decrease the blood flow by thickening the arteries.

The lung cancer mostly belongs to the SCLC category for about 10%-15%. The lung cancer will be highly damaging and the rapidly developing one is the SCLC which poses 10%-15% in proportion of lung cancer. Smoking of cigarette that has nicotine content and the deposition of toxins is the main cause of the lung cancer. The SCLC’s are identified only after it is rapidly spread over several parts of the body till a significant level. Among the range of lung cancer category, the NSCLC is the most affected and 85% of the portion is this case in the entire lung cancer cases.

Stages of NSCLC:

Stage I: Identification of cancer only in the lung zones. Stage II: Identification of cancer spread over the adjacent lymph nodes of the lung. Stage III: Identification of cancer developed towards the chest from the lungs and lymph nodes which is said to be the advanced stage. Stage IV: The entirely advanced stage. This state exists when the disease covers both the lungs and in the collection of other fluids inside the lungs or the development in other organs.

However, undergoing with the remedial treatment, around 30% - 55% of the patients who have NSCLC have a chance of reoccurrence and perish. Likewise, after surgery several lung cancer patients preferably sooner or later pass away cause of reoccurrence. Also, undergoing this treatment itself poses a high possibility of danger. Yet, the mortality associated treatment is a rare occurrence, still the persistence of hazards in death and the patients maximally will also meet with a reduced act after the surgical treatment. So, although with all the developed surgical treatments, the remedy for the cancer with the surgical removal of affected portions does not plays a vital role, the complete elimination of the affected portion is reasonable.

The proposed work is inspired to build the system with the performance of the computer to provide the support of spontaneous identification to make the medical decisions in an automated technique as its routine. And it should conclude with the procedures like detecting the disease at earlier stage with the radiologist’s portion which could effectively diagnose the patient’s scenario. Besides the prior detection of lung cancer presence, this work also subjects the significance of the reoccurrence of disease prediction before and after the surgical treatment undergone by the medical specialists either the radiation therapy way or the medical surgery.

The rest of the part are followed by various sections like, Section II: Introduction to automatic prediction of lung cancer of several research survey proposed by different scholars using classification section. Section III: Illustration of the proposed strategy. Section IV: Description of the evaluated results of the proposed technique. Section V: Conclusion of the work.

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According to the study of Cruz and Wishart, proposed and legalized revisions that the machine learning scheme significantly improves the cancer prediction exactness for about 15%-25% of its vulnerability, mortality and repetition than in ANN process. It also states that machine learning improves the elementary knowledge of the cancer progress and development.

The examinations of Yao et al., the cellular heterogeneity from varied cell types was been quantifiably illustrated by the progress of a computational approach in H&E marked compulsive images. They implied a deep learning approach for the classification of the cell subtype and then presented a reckonable feature to describe cellular information. They resulted on two lung cancer data sets survival models built from the clinical imaging biomarkers have better prediction power.

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