Mitigating Antibacterial Resistance Through Nanotechnology-Based Approaches

Mitigating Antibacterial Resistance Through Nanotechnology-Based Approaches

Priyanka Kriplani (Guru Gobind Singh College of Pharmacy, India), Vishnu Mittal (Independent Researcher, India), Bhawna Chopra (Independent Researcher, India), and Kumar Guarve (Independent Researcher, India)
DOI: 10.4018/979-8-3693-4139-1.ch004
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Abstract

A global hazard to public health has emerged from antibacterial resistance, leading to the need for innovative approaches to combat this issue. Nanotechnology has emerged as a promising field with various nanomaterials and nanodevices being developed to mitigate antibacterial resistance. Strategies based on nanotechnology have also concentrated on creating nanoscale biosensors for the quick identification of antibiotic resistance. A platform for creating new antibacterial agents, increasing targeted medication delivery, and developing better detection techniques is provided by nanoparticles, nanobiosensors, and nanomaterials. Future research and development projects utilizing nanotechnology-based methods may result in ground-breaking ways to tackle antibiotic resistance, eventually enhancing public health. High sensitivity and specificity provided by nanoscale sensors and devices enable early detection of bacteria that are multidrug resistant and facilitate specialized treatment approaches.
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Antibacterial Resistance

Antibacterial resistance is the capacity of bacteria to less susceptible to the actions of antibiotics, which makes treating illnesses brought on by these germs more challenging (Reygaert et al., 2018).

Background

Antibiotic resistance has quickly expanded around the world, raising concerns in the healthcare industry. Antibiotic misuse and overuse has increased bacterial resistance, lengthening hospital stays, boosting morbidity and death rates, and raising healthcare expenditures. Traditional approaches to combating antibacterial resistance, such the creation of new antibiotics, have been constrained by bacteria's capacity to swiftly adjust to current medications (Llor et al., 2014).

As a potential solution, nanotechnology offers new opportunities to combat antibacterial resistance. Nanomaterials, like nanoparticles and nanocomposites, possess unique properties at the nanoscale that can be utilized to overcome traditional limitations in antibiotic therapy. Nanotechnology-based approaches have shown promise in enhancing the effectiveness of existing antibiotics, enabling targeted drug delivery, disrupting bacterial biofilms, and providing alternative antimicrobial strategies (Mubeen et al., 2021).

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