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What is Basal Ganglia

Chapter 9
Medical Cannabis and the Effects of Cannabinoids on Fighting Cancer, Multiple Sclerosis, Epilepsy, Parkinson's, and Other Neurodegenerative Diseases
The term “basal ganglia” refers to a cluster of subcortical nuclei that serve a variety of tasks including motor learning, executive functions and behaviors, and emotions in addition to being largely in charge of motor control.
Published in Chapter:
Pros and Cons of Cannabinoids as a Potential Therapeutic Target for Treating Parkinson's Disease: Cannabinoid Receptor-Mediated Mechanism of Action
Mahesh Pattabhiramaiah (Bangalore University, India), Shanthala Mallikarjunaiah (Bangalore University, India), and Baishali Bedi Sarma (Bangalore University, Bangalore)
Copyright: © 2023 |Pages: 18
DOI: 10.4018/978-1-6684-5652-1.ch009
Abstract
Medical marijuana or cannabis is a psychedelic drug composed of highly lipophilic tetrahydrocannabinol (THC) and cannabidiol (CBD) components derived from the plant C. sativa and C. indica. Parkinson's disease (PD), in which interactivity of biochemical and cellular signaling pathways induces endogenous cannabinoid system, a neuromodulatory system, transmits specific physiological effects when coupled with G-protein-coupled receptor (GPCR) via type 1 cannabinoid receptor (CB1) and type 2 cannabinoid receptor (CB2). Much recent research indicates that interactions between the cannabis system and dopamine in the basal ganglia area diminish levodopa-induced dyskinesia (LID) and other symptoms. Due to the limited number of pharmacological treatment options presently available for PD, in-depth research with clinical trials are crucial in the search for molecules with therapeutic potential studies in a wide range of epidemiological work for PD to increase neural transmission. This chapter reviews the mode of action of cannabinoids in PD.
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Chapter 11
Metal Toxicity and Brain-Liver Axis: The Good, the Bad, and the Neurodegenerated
Group of structures (including caudate, putamen, and globus pallidus) mainly involved in voluntary and involuntary motor control.
Published in Chapter: Metal Toxicity and Brain-Liver Axis: The Good, the Bad, and the Neurodegenerated; From: Handbook of Research on Global Environmental Changes and Human Health
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