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What is Chemotherapy Agents

Environmental Exposures and Human Health Challenges
Technically, the term refers to therapeutic chemical treatment originally used as anti-infective term (for mercury and arsenic which were used before antibiotics were discovered) but most commonly, it is used for drugs or drug combinations used for treatment of cancer.
Published in Chapter:
Pharmaceuticals in Environment: Global Concerns and Regulations
Alka Bali (Panjab University, India)
Copyright: © 2019 |Pages: 27
DOI: 10.4018/978-1-5225-7635-8.ch013
Abstract
Pharmaceuticals and personal care products (PPCPs) constitute an integral part of modern healthcare systems which enter the environment through various routes. Because of their inherent biological activity, their presence in soil and the aquatic environment poses several eco-toxicological problems. Antibiotic contamination of soil and water bodies is leading to the development of microbial resistance to antibiotics and this has been recognized by several global bodies like WHO and EPA. Effective steps need to be taken in this regard including increased awareness, reduced pharmaceutical discharges in environment, green and sustainable pharmaceutical practice by pharmaceutical industry and healthcare professionals and improved remediation/bioremediation methods. This chapter outlines the various anticipated routes of exposure of pharmaceuticals to the environment along with their detrimental effects, fate and degradation in aquatic and terrestrial environments. The chapter also dwells upon the role of various regulatory bodies and plausible measures that may be adopted to alleviate the problem.
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