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What is Consensus Sequence

Chapter 22
Handbook of Research on Computational Methodologies in Gene Regulatory Networks
is a nucleotide sequence composed of the most frequently observed base at each position among several observed sequences.
Published in Chapter:
A Model for a Heterogeneous Genetic Network
Ângela T.F. Gonçalves (Darwin College, UK) and Ernesto J.F. Costa (Pólo II- Pinhal de Marrocos, Portugal)
Copyright: © 2010 |Pages: 23
DOI: 10.4018/978-1-60566-685-3.ch022
Abstract
In this chapter, we propose a new model for gene regulatory networks (GRN). The model incorporates more biological detail than other approaches, and is based on an artificial genome from which several products like genes, mRNA, miRNA, noncoding RNA, and proteins are extracted and connected, giving rise to a heterogeneous directed graph. We study the dynamics of the networks thus obtained, along with their topology (using degree distributions). Some considerations are made about the biological meaning of the outcome of the simulations.
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