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What is Long Term Potentiation

Chapter 67
Encyclopedia of Healthcare Information Systems
Long Term Potentiation is generally considered to represent a cellular mechanism underlying certain forms of learning and memory. Long term potentiation consists of an increase in the strength of a chemical synapse that lasts from minutes to several days or weeks following a series of short, high-frequency electrical stimuli.
Published in Chapter:
EONS an Online Synaptic Modeling Platform
Jean-Marie C. Bouteiller (University of Southern California, USA), Michel Baudry (University of Southern California, USA), and Theodore W. Berger (University of Southern California, USA)
Copyright: © 2008 |Pages: 7
DOI: 10.4018/978-1-59904-889-5.ch067
Abstract
The objective of the work presented here is to develop a computational tool designed specifically for the study of the complex mechanisms that occur at chemical synapses. This tool should enable students and researchers (biologists with very little training in computational biology, as well as experienced modelers) worldwide to study the roles of diverse parameters that impact synaptic transmission from presynaptic to postsynaptic depolarization in an integrated modeling platform, using an easy, user-friendly and modular graphical interface.
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