Nanoemulsion technique is categorized under the nano-technology and designed for quantifiable clinical and therapeutic application. The presently various nano-carriers-based nanoemulsions approach is widely targeted for a treat to various cancer. This therapy also overcomes various challenges such as low solubility, multidrug resistance, and toxicity, etc. Thus, nanoemulsions might be the solution to attain proficient and safe treatment of cancer. Nanoemuslison having several advantages such as nanometric size, ease of preparation, site-specific, drug encapsulation, non-immunogenic, biocompatibility, biodegradable, sustained and controlled release, large surface area, and thermodynamic stability, etc. Recently nanoemulsions are extensive investigated as drug carriers to improve the delivery rate of therapeutic agents or compounds. It will be formulated in a variety of forms such as liquids, sprays, foams, creams, ointments, and gels, etc. from mushroom bioactive components. All these potential developed nanoemulsions will be the great promising future of cosmetics, diagnostics, drug therapies, and biotechnologies.
Published in Chapter:
Mushroom-Derived Bioactive-Based Nanoemulsion: Current Status and Challenges for Cancer Therapy
Nagendra Kumar Chandrawanshi (Pt. Ravishankar Shukla University, India), Deepali Koreti (Pt. Ravishankar Shukla University, India), Anjali Kosre (Pt. Ravishankar Shukla University, India), and Pramod Kumar Mahish (Government Digvijay Autonomous Post Graduate College, Rajnandgaon, India)
Copyright: © 2022
|Pages: 23
DOI: 10.4018/978-1-7998-8378-4.ch016
Abstract
Cancer is a class of disorders that is characterized by the abnormal growth of cells in an uncontrolled manner. In cancer progression, tumor cells have become highly heterogeneous, and they create a mixed population of cells with different molecular characteristics. The mushroom bioactive compounds have a rich biological activity including immunomodulatory, anticarcinogenic, antiviral, antioxidant, and anti-inflammatory, etc. Besides, conventional anticancer drugs and applied therapy have tremendous challenges and limitations such as poor solubility, narrow therapeutic window, cytotoxicity to normal tissues, etc., which may be the causes of treatment failure in cancer. A previous study reported mushroom bioactive compounds against cancer treatment. The chapter focuses on mushroom-derived bioactive compounds and possible implications in nanotechnology and, further, will be utilized for new advanced nanoemulsion techniques for the promising treatment of cancer.