What is Stem Cell Transplantation

This chapter focuses on genetic disorders affecting the human circulatory system. Genetic disorders can occur due to a defect in a single gene or in a set of genes. The body's circulatory system is made up of the heart and blood vessels (arteries, arterioles, veins, venules, and capillaries). The system carries both blood and lymphatic fluid in two circuits: pulmonary circulation (blood through the lungs for oxygenation) and systemic circuits (from the heart to all body parts). Fourteen disorders are presented in this chapter including sickle cell disease, Gaucher Disease, chronic myeloid leukaemia, Niemann-Pick Disease, haemophilia, atherosclerosis, ataxia telangiectasia, haemoglobinuria, thalassemia, William's syndrome, porphyria, long QT syndrome, and alpha-I-antitrypsin deficiency.