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Nanocarriers for Vaccine and Gene Delivery Application

Nanocarriers for Vaccine and Gene Delivery Application

Behiye Şenel, Gülay Büyükköroğlu
Copyright: © 2018 |Pages: 34
ISBN13: 9781522547815|ISBN10: 1522547819|EISBN13: 9781522547822
DOI: 10.4018/978-1-5225-4781-5.ch014
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MLA

Şenel, Behiye, and Gülay Büyükköroğlu. "Nanocarriers for Vaccine and Gene Delivery Application." Multifunctional Nanocarriers for Contemporary Healthcare Applications, edited by Md. Abul Barkat, et al., IGI Global, 2018, pp. 381-414. https://doi.org/10.4018/978-1-5225-4781-5.ch014

APA

Şenel, B. & Büyükköroğlu, G. (2018). Nanocarriers for Vaccine and Gene Delivery Application. In M. Barkat, H. A.B., S. Beg, & F. Ahmad (Eds.), Multifunctional Nanocarriers for Contemporary Healthcare Applications (pp. 381-414). IGI Global. https://doi.org/10.4018/978-1-5225-4781-5.ch014

Chicago

Şenel, Behiye, and Gülay Büyükköroğlu. "Nanocarriers for Vaccine and Gene Delivery Application." In Multifunctional Nanocarriers for Contemporary Healthcare Applications, edited by Md. Abul Barkat, et al., 381-414. Hershey, PA: IGI Global, 2018. https://doi.org/10.4018/978-1-5225-4781-5.ch014

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Abstract

Nanocarriers with various compositions and biological properties are frequently used systems for in-vitro/in-vivo vaccination and gene transfer. In recent years, developments in nanotechnology have focused on the design and synthesis of nanocarriers that have new properties and can be modified for gene and vaccine delivery. In the favorable results obtained from in-vivo studies performed, they increase interest in these developments and pave the way for their therapeutic use. Nanocarriers have become increasingly important because they can stabilize vaccine antigens and serve as adjuvants, with the advantage of easily transporting genetic material to the target site. In nanocarriers, the molecules involved are adsorbed to the surface or encapsulated in particulates. At the same time, surface modification of nanoparticles allows these systems to carry cargo molecules easily to target site. Among the most studied nanocarriers, lipidic and polymeric systems dendrimers, inorganic nanoparticles, cyclodextrins, cell penetration peptides, and ISCOMs are attracting attention.

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