Recent Advances and Neural Connectivity in Autism

Recent Advances and Neural Connectivity in Autism

Kiran Srivastava, Lalit Kumar Singh
ISBN13: 9781522570042|ISBN10: 1522570047|EISBN13: 9781522570059
DOI: 10.4018/978-1-5225-7004-2.ch006
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MLA

Srivastava, Kiran, and Lalit Kumar Singh. "Recent Advances and Neural Connectivity in Autism." Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders, edited by Sanjeev Kumar Gupta, et al., IGI Global, 2019, pp. 102-124. https://doi.org/10.4018/978-1-5225-7004-2.ch006

APA

Srivastava, K. & Singh, L. K. (2019). Recent Advances and Neural Connectivity in Autism. In S. Gupta, S. Venkatesan, S. Goswami, & R. Kumar (Eds.), Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders (pp. 102-124). IGI Global. https://doi.org/10.4018/978-1-5225-7004-2.ch006

Chicago

Srivastava, Kiran, and Lalit Kumar Singh. "Recent Advances and Neural Connectivity in Autism." In Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders, edited by Sanjeev Kumar Gupta, et al., 102-124. Hershey, PA: IGI Global, 2019. https://doi.org/10.4018/978-1-5225-7004-2.ch006

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Abstract

The current chapter has reviewed the functional and structural brain connectivity in children with autism spectrum disorders (ASD). Neuropathological studies of the cerebral cortex in autism indicate abnormalities of synaptic and columnar structure and of neuronal migration. The MRI morphometry in young children with autism reveals excessive volume of cerebrum or cerebral white matter or increased total brain volume. The absence of such a volume difference in adults suggests that early hyperplasia in autism is followed by a plateau during which brain growth in normal subjects catches up. The developmental course of brain connectivity and the categorization potential of different connectivity process are important topics that are investigated by different studies. Finally, several studies contribute to a better understanding of the links between cellular abnormalities in the autistic cortex (both cerebral and cerebellar) and disturbances in network connectivity.

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