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Gene Therapy and Gene Editing for Cancer Therapeutics

Gene Therapy and Gene Editing for Cancer Therapeutics

Shubhjeet Mandal, Piyush Kumar Tiwari
Copyright: © 2021 |Pages: 89
ISBN13: 9781799865308|ISBN10: 1799865304|EISBN13: 9781799865315
DOI: 10.4018/978-1-7998-6530-8.ch004
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MLA

Mandal, Shubhjeet, and Piyush Kumar Tiwari. "Gene Therapy and Gene Editing for Cancer Therapeutics." Handbook of Research on Advancements in Cancer Therapeutics, edited by Sumit Kumar, et al., IGI Global, 2021, pp. 116-204. https://doi.org/10.4018/978-1-7998-6530-8.ch004

APA

Mandal, S. & Tiwari, P. K. (2021). Gene Therapy and Gene Editing for Cancer Therapeutics. In S. Kumar, M. Rizvi, & S. Verma (Eds.), Handbook of Research on Advancements in Cancer Therapeutics (pp. 116-204). IGI Global. https://doi.org/10.4018/978-1-7998-6530-8.ch004

Chicago

Mandal, Shubhjeet, and Piyush Kumar Tiwari. "Gene Therapy and Gene Editing for Cancer Therapeutics." In Handbook of Research on Advancements in Cancer Therapeutics, edited by Sumit Kumar, Moshahid Alam Rizvi, and Saurabh Verma, 116-204. Hershey, PA: IGI Global, 2021. https://doi.org/10.4018/978-1-7998-6530-8.ch004

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Abstract

Over the past two decades, developments in human genomics have shown that cancer in the host genome is caused by somatic aberration. This discovery has inspired interest among cancer researchers; many are now using genetic engineering therapeutic methods to improve the cancer regression and seeking a possible cure for the disease. The large gene therapy sector offers a variety of therapies which are likely to become effective in preventing cancer deaths. The latest clinical trials of third generation vaccines for a wide variety of cancers have produced promising results. Cancer virotherapy, which uses viral particles replicating within the cancer cell, is an emerging method of treatment which shows great promise. The latest developments in gene editing techniques, such as CRISPR, Cas9, TALENs, and ZFNs, are being used to help to make cancer a manageable condition. Gene therapy is expected to play a significant role in potential cancer therapy as a part of a multi-modality procedure.

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