Welcome to the InfoSci Platform
Cognitive Function Involving Glial Cells: The Surprising Role of Astrocytes

Cognitive Function Involving Glial Cells: The Surprising Role of Astrocytes

Samira Boulbaroud, Hanane Khalki, Fatima Zahra Azzaoui
Copyright: © 2024 |Pages: 28
ISBN13: 9781668496756|ISBN10: 1668496755|ISBN13 Softcover: 9798369347386|EISBN13: 9781668496763
DOI: 10.4018/978-1-6684-9675-6.ch003
Cite Chapter Cite Chapter

MLA

Boulbaroud, Samira, et al. "Cognitive Function Involving Glial Cells: The Surprising Role of Astrocytes." Physiology and Function of Glial Cells in Health and Disease, edited by Bilal El-Mansoury, et al., IGI Global, 2024, pp. 32-59. https://doi.org/10.4018/978-1-6684-9675-6.ch003

APA

Boulbaroud, S., Khalki, H., & Azzaoui, F. Z. (2024). Cognitive Function Involving Glial Cells: The Surprising Role of Astrocytes. In B. El-Mansoury, O. El Hiba, & A. Jayakumar (Eds.), Physiology and Function of Glial Cells in Health and Disease (pp. 32-59). IGI Global. https://doi.org/10.4018/978-1-6684-9675-6.ch003

Chicago

Boulbaroud, Samira, Hanane Khalki, and Fatima Zahra Azzaoui. "Cognitive Function Involving Glial Cells: The Surprising Role of Astrocytes." In Physiology and Function of Glial Cells in Health and Disease, edited by Bilal El-Mansoury, Omar El Hiba, and Arumugam Radhakrishnan Jayakumar, 32-59. Hershey, PA: IGI Global, 2024. https://doi.org/10.4018/978-1-6684-9675-6.ch003

Export Reference

Mendeley
Favorite

Abstract

Astrocytes, once considered passive support cells in the central nervous system, are now recognized as dynamic contributors to neuronal processes. They play pivotal roles in regulating synaptic transmission, modulating excitability, and influencing synapse formation. These non-neuronal cells release gliotransmitters like glutamate, affecting synaptic activity. Dysfunctions in astrocytes are linked to neurodegenerative and psychiatric disorders. In neurodegenerative disorders like Alzheimer's and Parkinson's, astrocytic dysfunction plays distinct roles. While astrocytes may not significantly contribute to Alzheimer's progression, they are involved in neuroinflammation, Aβ metabolism, and calcium regulation. Conversely, in Parkinson's, astrocytes contribute to mitochondrial dysfunction, impacting dopaminergic neurons. This comprehensive exploration sheds light on the intricate and multifaceted roles of astrocytes in cognition and their potential implications for therapeutic interventions in neurological and psychiatric conditions.

Request Access

You do not own this content. Please login to recommend this title to your institution's librarian or purchase it from the IGI Global bookstore.