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Intravascular Imaging and Haemodynamics: The Role of Shear Stress in Atherosclerosis and In-Stent Restenosis

Intravascular Imaging and Haemodynamics: The Role of Shear Stress in Atherosclerosis and In-Stent Restenosis

Michail I. Papafaklis, Lampros K. Michalis
Copyright: © 2012 |Pages: 23
ISBN13: 9781613500958|ISBN10: 1613500955|EISBN13: 9781613500965
DOI: 10.4018/978-1-61350-095-8.ch019
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MLA

Papafaklis, Michail I., and Lampros K. Michalis. "Intravascular Imaging and Haemodynamics: The Role of Shear Stress in Atherosclerosis and In-Stent Restenosis." Intravascular Imaging: Current Applications and Research Developments, edited by Vasilios D. Tsakanikas, et al., IGI Global, 2012, pp. 326-348. https://doi.org/10.4018/978-1-61350-095-8.ch019

APA

Papafaklis, M. I. & Michalis, L. K. (2012). Intravascular Imaging and Haemodynamics: The Role of Shear Stress in Atherosclerosis and In-Stent Restenosis. In V. Tsakanikas, L. Michalis, D. Fotiadis, K. Naka, & C. Bourantas (Eds.), Intravascular Imaging: Current Applications and Research Developments (pp. 326-348). IGI Global. https://doi.org/10.4018/978-1-61350-095-8.ch019

Chicago

Papafaklis, Michail I., and Lampros K. Michalis. "Intravascular Imaging and Haemodynamics: The Role of Shear Stress in Atherosclerosis and In-Stent Restenosis." In Intravascular Imaging: Current Applications and Research Developments, edited by Vasilios D. Tsakanikas, et al., 326-348. Hershey, PA: IGI Global, 2012. https://doi.org/10.4018/978-1-61350-095-8.ch019

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Abstract

Shear stress on the endothelial surface has been implicated in atherosclerosis localization, plaque vulnerability, and remodeling behavior of the arterial wall, as well as in-stent restenosis following percutaneous coronary interventions. The purposes of this chapter are to introduce haemodynamic shear stress, briefly explain the methodology for measuring and imaging shear stress in vivo, present the role of shear stress in the atherosclerotic disease process, and cite the evidence highlighting the effects of stent implantation on local blood flow patterns and linking shear stress at the stent surface to neointimal hyperplasia following coronary artery stenting.

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