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Introduction to the CFM and the Clinical Applications

Introduction to the CFM and the Clinical Applications

Denis Azzopardi
Copyright: © 2012 |Pages: 22
ISBN13: 9781466609754|ISBN10: 1466609753|EISBN13: 9781466609761
DOI: 10.4018/978-1-4666-0975-4.ch010
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MLA

Azzopardi, Denis. "Introduction to the CFM and the Clinical Applications." Neonatal Monitoring Technologies: Design for Integrated Solutions, edited by Wei Chen, et al., IGI Global, 2012, pp. 222-243. https://doi.org/10.4018/978-1-4666-0975-4.ch010

APA

Azzopardi, D. (2012). Introduction to the CFM and the Clinical Applications. In W. Chen, S. Oetomo, & L. Feijs (Eds.), Neonatal Monitoring Technologies: Design for Integrated Solutions (pp. 222-243). IGI Global. https://doi.org/10.4018/978-1-4666-0975-4.ch010

Chicago

Azzopardi, Denis. "Introduction to the CFM and the Clinical Applications." In Neonatal Monitoring Technologies: Design for Integrated Solutions, edited by Wei Chen, Sidarto Bambang Oetomo, and Loe Feijs, 222-243. Hershey, PA: IGI Global, 2012. https://doi.org/10.4018/978-1-4666-0975-4.ch010

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Abstract

The cerebral function monitor is a device for trend monitoring of changes in the amplitude of the electroencephalogram, typically recorded from 1-2 pairs of electrodes. Initially developed and introduced to monitor cerebral activity in encephalopathic adult patients or during anaesthesia it is now most widely used in newborns with encephalopathy to assess the severity of encephalopathy and for prognosis. The time to recovery from a moderately/severely abnormal amplitude integrated electroencephalogram trace to a normal trace is strongly predictive of subsequent neurological outcome following neonatal hypoxic ischaemic encephalopathy, including in newborns receiving neuroprotective treatment with prolonged moderate hypothermia. The cerebral function monitor is also used for seizure detection and to monitor response to anticonvulsant therapies. Amplitude integrated electroencephalography compares well with standard electroencephalography when used to assess the severity of neonatal encephalopathy but a standard electroencephalogram is still required to provide additional important information about changes in frequency, and in the synchrony and distribution and other characteristics of cerebral cortical activity. The role of the amplitude integrated electroencephalogram to identify brain injury in preterm infants remains to be determined.

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