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BMP Signaling in Regenerative Medicine

BMP Signaling in Regenerative Medicine

Julia Zimmer, Elisa Degenkolbe, Britt Wildemann, Petra Seemann
Copyright: © 2013 |Pages: 30
ISBN13: 9781466636040|ISBN10: 1466636041|EISBN13: 9781466636057
DOI: 10.4018/978-1-4666-3604-0.ch064
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MLA

Zimmer, Julia, et al. "BMP Signaling in Regenerative Medicine." Bioinformatics: Concepts, Methodologies, Tools, and Applications, edited by Information Resources Management Association, IGI Global, 2013, pp. 1252-1281. https://doi.org/10.4018/978-1-4666-3604-0.ch064

APA

Zimmer, J., Degenkolbe, E., Wildemann, B., & Seemann, P. (2013). BMP Signaling in Regenerative Medicine. In I. Management Association (Ed.), Bioinformatics: Concepts, Methodologies, Tools, and Applications (pp. 1252-1281). IGI Global. https://doi.org/10.4018/978-1-4666-3604-0.ch064

Chicago

Zimmer, Julia, et al. "BMP Signaling in Regenerative Medicine." In Bioinformatics: Concepts, Methodologies, Tools, and Applications, edited by Information Resources Management Association, 1252-1281. Hershey, PA: IGI Global, 2013. https://doi.org/10.4018/978-1-4666-3604-0.ch064

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Abstract

More than 40 years after the discovery of Bone Morphogenetic Proteins (BMPs) as bone inducers, a whole protein family of growth factors connected to a wide variety of functions in embryonic development, homeostasis, and regeneration has been characterized. Today, BMP2 and BMP7 are already used in the clinic to promote vertebral fusions and restoration of non-union fractures. Besides describing present clinical applications, the authors review ongoing trials highlighting the future possibilities of BMPs in medicine. Apparently, the physiological roles of BMPs have expanded their range from bone growth induction and connective tissue regeneration to cancer diagnosis/treatment and cardiovascular disease prevention.

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