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Myocardial Infarction: Disease Mechanisms and Therapeutic Perspectives

Myocardial Infarction: Disease Mechanisms and Therapeutic Perspectives

Kalyan C. Chapalamadugu, Samhitha Gudla, Rakesh Kukreja, Srinivas M. Tipparaju
Copyright: © 2017 |Pages: 22
ISBN13: 9781522520924|ISBN10: 1522520929|EISBN13: 9781522520931
DOI: 10.4018/978-1-5225-2092-4.ch008
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MLA

Chapalamadugu, Kalyan C., et al. "Myocardial Infarction: Disease Mechanisms and Therapeutic Perspectives." Emerging Applications, Perspectives, and Discoveries in Cardiovascular Research, edited by Ashim Malhotra and Shivani Soni, IGI Global, 2017, pp. 139-160. https://doi.org/10.4018/978-1-5225-2092-4.ch008

APA

Chapalamadugu, K. C., Gudla, S., Kukreja, R., & Tipparaju, S. M. (2017). Myocardial Infarction: Disease Mechanisms and Therapeutic Perspectives. In A. Malhotra & S. Soni (Eds.), Emerging Applications, Perspectives, and Discoveries in Cardiovascular Research (pp. 139-160). IGI Global. https://doi.org/10.4018/978-1-5225-2092-4.ch008

Chicago

Chapalamadugu, Kalyan C., et al. "Myocardial Infarction: Disease Mechanisms and Therapeutic Perspectives." In Emerging Applications, Perspectives, and Discoveries in Cardiovascular Research, edited by Ashim Malhotra and Shivani Soni, 139-160. Hershey, PA: IGI Global, 2017. https://doi.org/10.4018/978-1-5225-2092-4.ch008

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Abstract

Myocardial infarction (MI) is a major cardiovascular disease (CVD) and ranks among the leading causes of morbidity and mortality in humans, worldwide. Despite advances in disease prevention and treatment strategies, majority of the developed and developing world's suffer higher disease burden from MI, and incur billions of dollars in healthcare costs (Murray et al., 2015). Global estimates from 2013 show that MI is the major cardiovascular disease (CVD), and that deaths due to MI accounted for nearly half of the 17 million CVD mortalities (GBD, 2013; Mortality and Causes of Death Collaborators, 2015). Within the United States, MI top's the chart of both communicable and non-communicable diseases in terms of health loss that it is estimated to have inflicted in the population (Murray, et al., 2015). It has been estimated that every 2 minutes, three Americans suffer from myocardial infarction (MI), primary cause of MI being coronary blood flow obstruction and myocardial damage. The annual estimates of MI incidence in USA are approximately three quarter million a year while almost two-thirds of these cases represent new attacks (Mozaffarian, et al., 2015). Collectively, MI continues to lead the charts for CVD incidence rates, health loss, mortalities thereby putting enormous strain on healthcare system.

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