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Biocompatible Carbon Nanodots for Functional Imaging and Cancer Therapy: Carbon Nanodots for Imaging and Cancer Therapy

Biocompatible Carbon Nanodots for Functional Imaging and Cancer Therapy: Carbon Nanodots for Imaging and Cancer Therapy

Alexandre Roumenov Loukanov, Hristo Stefanov Gagov, Milena Yankova Mishonova, Seiichiro Nakabayashi
Copyright: © 2018 |Volume: 7 |Issue: 2 |Pages: 15
ISSN: 2161-1610|EISSN: 2161-1629|EISBN13: 9781522546726|DOI: 10.4018/IJBCE.2018070103
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MLA

Loukanov, Alexandre Roumenov, et al. "Biocompatible Carbon Nanodots for Functional Imaging and Cancer Therapy: Carbon Nanodots for Imaging and Cancer Therapy." IJBCE vol.7, no.2 2018: pp.31-45. http://doi.org/10.4018/IJBCE.2018070103

APA

Loukanov, A. R., Gagov, H. S., Mishonova, M. Y., & Nakabayashi, S. (2018). Biocompatible Carbon Nanodots for Functional Imaging and Cancer Therapy: Carbon Nanodots for Imaging and Cancer Therapy. International Journal of Biomedical and Clinical Engineering (IJBCE), 7(2), 31-45. http://doi.org/10.4018/IJBCE.2018070103

Chicago

Loukanov, Alexandre Roumenov, et al. "Biocompatible Carbon Nanodots for Functional Imaging and Cancer Therapy: Carbon Nanodots for Imaging and Cancer Therapy," International Journal of Biomedical and Clinical Engineering (IJBCE) 7, no.2: 31-45. http://doi.org/10.4018/IJBCE.2018070103

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Abstract

This article describes how carbon quantum dots (C-dots) are tiny carbon nanoparticles (less than 10 nm in size) being envisaged to be used in bio-sensing, bio-imaging and drug delivery nanosystems. Their low toxicity and stable chemical properties make them suitable candidates for new types of fluorescent probe, which overcome the common drawbacks of previous fluorescent probes (organic dyes and inorganic quantum dots). In addition, fluorescent C-dots possess a rather strong ability to bind with other organic and inorganic molecules due to their abundant surface groups. For that reason, fluorescent C-dots can be manipulated via series of controllable chemical treatments in order to satisfy the demands in the photocatalytic, biochemical and chemical sensing, bio-imaging, drug delivery and enhanced cell targeting. In recent studies it was described the development of carbon quantum dots with large two-photon absorption cross sections towards two-photon imaging for use in photodynamic cancer therapy. Thus, C-dots have become a rising star in biomedical research with a promising future for the application in nanomedicine.

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