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Gastrointestinal Tract and COVID-19: Insights Into the Role of Gut Microbiome

Gastrointestinal Tract and COVID-19: Insights Into the Role of Gut Microbiome

Aaron Lelo Pambu, Abdellah Zinedine
Copyright: © 2022 |Pages: 14
ISBN13: 9781799882251|ISBN10: 179988225X|EISBN13: 9781799882268
DOI: 10.4018/978-1-7998-8225-1.ch008
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MLA

Pambu, Aaron Lelo, and Abdellah Zinedine. "Gastrointestinal Tract and COVID-19: Insights Into the Role of Gut Microbiome." Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19, edited by Omar El Hiba, et al., IGI Global, 2022, pp. 127-140. https://doi.org/10.4018/978-1-7998-8225-1.ch008

APA

Pambu, A. L. & Zinedine, A. (2022). Gastrointestinal Tract and COVID-19: Insights Into the Role of Gut Microbiome. In O. El Hiba, J. Radhakrishnan, T. Balzano, & F. Isbaine (Eds.), Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 (pp. 127-140). IGI Global. https://doi.org/10.4018/978-1-7998-8225-1.ch008

Chicago

Pambu, Aaron Lelo, and Abdellah Zinedine. "Gastrointestinal Tract and COVID-19: Insights Into the Role of Gut Microbiome." In Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19, edited by Omar El Hiba, et al., 127-140. Hershey, PA: IGI Global, 2022. https://doi.org/10.4018/978-1-7998-8225-1.ch008

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Abstract

The current outbreak of the novel coronavirus, SARS-CoV-2 (coronavirus disease 2019; previously 2019- nCoV), epi-centered in Hubei Province of the People's Republic of China, has spread to many other countries caused an extreme burden for healthcare systems globally. Coronaviruses are traditionally considered nonlethal pathogens to humans, mainly causing approximately 15% of common colds. In this century, we have encountered highly pathogenic human CoVs twice. In this chapter, the authors propose to focus the gastrointestinal physiopathology of the infection of SARS-Cov2. This chapter will develop subject like the gastrointestinal manifestations of the infection to SARS-Cov2. The second part of this chapter will develop the role of the gut microbiome in the SARS-Cov2 diseases susceptibilities. And then the authors will show the etiopathogenesis of SARS-Cov2 associated diarrhea. As reported by previous studies, the SARS-Cov virus entry into host cell is mediated by the interaction between the envelop-anchored viral spike protein and the host receptor named angiotensin-converting enzyme 2 (ACE2).

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