Welcome to the InfoSci Platform
Probiotics, Gut Microbiota, and Epigenomics: A Review of Pre-Clinical and Clinical Investigations

Probiotics, Gut Microbiota, and Epigenomics: A Review of Pre-Clinical and Clinical Investigations

Mohd Iqbal Bhat, Shabina Rashid
Copyright: © 2023 |Pages: 19
ISBN13: 9781799841203|ISBN10: 1799841200|EISBN13: 9781799841210
DOI: 10.4018/978-1-7998-4120-3.ch008
Cite Chapter Cite Chapter

MLA

Bhat, Mohd Iqbal, and Shabina Rashid. "Probiotics, Gut Microbiota, and Epigenomics: A Review of Pre-Clinical and Clinical Investigations." Exploring Complementary and Alternative Medicinal Products in Disease Therapy, edited by Etetor Roland Eshiet, IGI Global, 2023, pp. 192-210. https://doi.org/10.4018/978-1-7998-4120-3.ch008

APA

Bhat, M. I. & Rashid, S. (2023). Probiotics, Gut Microbiota, and Epigenomics: A Review of Pre-Clinical and Clinical Investigations. In E. Eshiet (Ed.), Exploring Complementary and Alternative Medicinal Products in Disease Therapy (pp. 192-210). IGI Global. https://doi.org/10.4018/978-1-7998-4120-3.ch008

Chicago

Bhat, Mohd Iqbal, and Shabina Rashid. "Probiotics, Gut Microbiota, and Epigenomics: A Review of Pre-Clinical and Clinical Investigations." In Exploring Complementary and Alternative Medicinal Products in Disease Therapy, edited by Etetor Roland Eshiet, 192-210. Hershey, PA: IGI Global, 2023. https://doi.org/10.4018/978-1-7998-4120-3.ch008

Export Reference

Mendeley
Favorite

Abstract

Probiotics therapy has emerged as a popular, potential alternative therapy utilized in combating disorders associated with mammalian gut and visceral organs. Ongoing research suggests that probiotics directly or indirectly modulate host epigenomic signatures that in turn affect the host functional outcome. Data obtained from experimental studies indicate that microbiota, diet, and pharmaceuticals affect host epigenetic machinery subsequently resulting in specific physiological responses. Thus, molecular designing of epigenetic-based therapeutic agents may provide a valid pathway to rectifying aberrant changes and managing disease risk and progression. Recent investigations show that probiotic intervention mitigates uncharacteristic epigenetic changes that are associated with many health complications. However, stakeholders need to recognize that probiotic research is an emerging field; therefore, this science must undergo extensive mechanistic investigation. This chapter highlights the potential probiotic mediated host epigenomic interventions in disease therapy and management.

Request Access

You do not own this content. Please login to recommend this title to your institution's librarian or purchase it from the IGI Global bookstore.