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Executive Dysfunction in Parkinson’s Disease

Executive Dysfunction in Parkinson’s Disease

Satoshi Kamei
Copyright: © 2013 |Pages: 9
ISBN13: 9781466621138|ISBN10: 1466621133|EISBN13: 9781466621145
DOI: 10.4018/978-1-4666-2113-8.ch002
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MLA

Kamei, Satoshi. "Executive Dysfunction in Parkinson’s Disease." Biomedical Engineering and Cognitive Neuroscience for Healthcare: Interdisciplinary Applications, edited by Jinglong Wu, IGI Global, 2013, pp. 11-19. https://doi.org/10.4018/978-1-4666-2113-8.ch002

APA

Kamei, S. (2013). Executive Dysfunction in Parkinson’s Disease. In J. Wu (Ed.), Biomedical Engineering and Cognitive Neuroscience for Healthcare: Interdisciplinary Applications (pp. 11-19). IGI Global. https://doi.org/10.4018/978-1-4666-2113-8.ch002

Chicago

Kamei, Satoshi. "Executive Dysfunction in Parkinson’s Disease." In Biomedical Engineering and Cognitive Neuroscience for Healthcare: Interdisciplinary Applications, edited by Jinglong Wu, 11-19. Hershey, PA: IGI Global, 2013. https://doi.org/10.4018/978-1-4666-2113-8.ch002

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Abstract

Executive dysfunction (ExD) constitutes a core feature of the cognitive impairment in Parkinson’s disease (PD). ExD in non-demented PD was evaluated using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provided for the first time a broad assessment of ExD in PD patients. ExD in non-demented PD patients are predisposed to a greater severity of PD, particularly in impairments in activities of daily living. Patients with non-demented PD exhibited a wide range of ExD symptoms. All components of ExD were correlated with severity of PD, but correlation patterns differed across components. The first quantitative EEG evaluation of the differences between PD with and without ExD was also described. PD with ExD exhibited an increase in slow wave activity and a decrease in alpha and fast wave activities in frontal pole and frontal locations. These findings suggest that the ExD in PD is caused by frontal dysfunction.

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