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Modularity of Biochemical Networks

Modularity of Biochemical Networks

Hiroyuki Kurata
Copyright: © 2013 |Pages: 11
ISBN13: 9781466621961|ISBN10: 1466621966|EISBN13: 9781466621978
DOI: 10.4018/978-1-4666-2196-1.ch033
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MLA

Kurata, Hiroyuki. "Modularity of Biochemical Networks." Technological Advancements in Biomedicine for Healthcare Applications, edited by Jinglong Wu, IGI Global, 2013, pp. 336-346. https://doi.org/10.4018/978-1-4666-2196-1.ch033

APA

Kurata, H. (2013). Modularity of Biochemical Networks. In J. Wu (Ed.), Technological Advancements in Biomedicine for Healthcare Applications (pp. 336-346). IGI Global. https://doi.org/10.4018/978-1-4666-2196-1.ch033

Chicago

Kurata, Hiroyuki. "Modularity of Biochemical Networks." In Technological Advancements in Biomedicine for Healthcare Applications, edited by Jinglong Wu, 336-346. Hershey, PA: IGI Global, 2013. https://doi.org/10.4018/978-1-4666-2196-1.ch033

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Abstract

To reveal the relationships between large-scale, heterogeneous biochemical networks and their associated functions, called design principles in biology, it is critically important to disintegrate the networks into topology- or function-based subnetworks to analyze the mechanism of how each subnetwork generates a specific biological function, and to synthesize them as the whole system in the same manner as engineering, where a variety of parts are assembled into functional machines. This synthesis and analysis approach can be carried out by a computer. In this review, the author describes several methodologies that serve to disintegrate biological systems into biologically meaningful modules, with practical consequences for systems biology studies.

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