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Providing optimal care to patients is a primary concern in the healthcare field. By utilizing the latest resources and research in biomedical applications, the needs and expectations of patients can be successfully exceeded. Novel Approaches for Drug Delivery is an authoritative reference source for...

Technological innovations have become the impetus for continuous developments in medical research. With the assistance of new technologies, effective drug delivery techniques have been improved for optimal patient care. Recent Advances in Drug Delivery Technology is a pivotal reference source for the...

The delivery of optimal pharmaceutical services to patients is a pivotal concern in the healthcare field. By examining current trends and techniques in the industry, processes can be maintained and improved. Pharmaceutical Sciences: Breakthroughs in Research and Practice provides comprehensive coverage...

Lipid vesicular systems composed of hydrated amphihiles with or without bilayer inducing agents such as cholesterol. On the basis of used amphiphilic molecule different nomenclature are used as liposomes, ufasomes and niosomes. Nonionic surfactants with mono-, di- or trialkyl chains form niosomes which...

Pharmacosomes are the colloidal dispersions of drugs covalently bound to lipids and may exist as ultrafine vesicular, micellar or hexagonal aggregates, depending on the chemical structure of the drug lipid complex. The term pharmacosomes is explicitly used to describe the zwitterion, amphiphilic...

The latest development in the field of smart hydrogels application as drugs carriers is shown in this chapter. Hydrogels are three-dimensional polymer network consisting of at least one hydrophilic monomer. They are insoluble in water, but in the excess presence of water or physiological fluids, swell...

This chapter characterizes need for new patient-specific approaches in medicine. The authors here illustrate role of nanomedicine and particularly nanotheranostics, combining diagnostic and therapeutic functions, in the paradigm of personalized disease treatment. This chapter discusses current insights...

Cosmeceuticals are topical cosmetic-pharmaceutical hybrids used to maintain and improve appearance and beauty of the skin. The strong demand from the consumers to constantly look youthful and flawless has driven the research and development as well as sale volume of cosmeceuticals. Present studies show...

In this pharma innovative world, there are more than 30 drug delivery systems. Today's due to lacking the target specificity, the present scenario about drug delivery is emphasizing towards targeted drug delivery systems. Erythrocytes are the most common type of blood cells travel thousands of...

Pharmacogenomics deals with drug responses in individual based on genetic variation in genome. Based on genetic variations, drugs may produce more or less therapeutic effect, and same way in side effects also. Physicians can use information about your genetic makeup to choose those drugs and drug doses...

Small colloidal particles having their diameter in the range of 50 to 500nm are defined as Nanoparticles. These are usually prepared either by using biodegradable or non-biodegradable polymers and are usually classified in two broad categories: (1) Nanocapsules: a type of reservoir system in which an...

Advancements in cancer drug delivery have led to the development of personalized oncology care through molecularly-driven targeted therapies. Understanding molecular and cellular mechanisms which drive tumor progression and resistance is critical in managing new treatment strategies which have shifted...

Within the last quarter century, technology has been a major catalyst of the advancement in various fields of scientific knowledge, particularly medical research. This new enlightenment has spurred the exploration of alternative treatment methods to some of society's most problematic diseases. One...

Bioinformatics has emerged as a major element in contemporary biomedical and pharmaceutical region. Bioinformatics deals with growth in biological data and has led to development of many databases. Bioinformatics deals with collection of data that is relevant clinically and these days separate term...

In this pharma innovative world, there are more than 30 drug delivery systems. Today's due to lacking the target specificity, the present scenario about drug delivery is emphasizing towards targeted drug delivery systems. Erythrocytes are the most common type of blood cells travel thousands of...

Diabetes Mellitus is one of the major healthcare problems faced by the society today and has become alarmingly epidemic in many parts of the world. Despite enormous knowledge and technology advancement, available diabetes therapeutics only provide symptomatic relief by reducing blood glucose level...

In this chapter, the methodology of building up quantitative structure—property/activity relationships (QSPRs/QSARs)—by means of the CORAL software is described. The Monte Carlo method is the basis of this approach. Simplified Molecular Input-Line Entry System (SMILES) is used as the representation of...

Molecular dynamics simulation is an important tool to capture the dynamicity of biological molecule and the atomistic insights. These insights are helpful to explore biological functions. Molecular dynamics simulation from femto seconds to milli seconds scale give a large ensemble of conformations that...

A most challenging part in docking-based virtual screening is the scoring functions implemented in various docking programs in order to evaluate different poses of the ligands inside the binding cavity of the receptor. Precise and trustable measurement of ligand-protein affinity for Structure-Based...

Protein-protein docking algorithms are powerful computational tools, capable of analyzing the protein-protein interactions at the atomic-level. In this chapter, we will review the theoretical concepts behind different protein-protein docking algorithms, highlighting their strengths as well as their...

Most of the developed kinase inhibitor drugs are ATP competitive and suffer from drawbacks such as off-target kinase activity, development of resistance due to mutation in the ATP binding pocket and unfavorable intellectual property situations. Besides the ATP binding pocket, protein kinases have...

Smart and intelligent computational methods are essential nowadays for designing, manufacturing and optimizing new drugs. New and innovative computational tools and algorithms are consistently developed and applied for the development of novel therapeutic compounds in many research projects. Rapid...

The tremendous success in developing new nanomaterials and fostering technological innovation arises from the focus on interdisciplinary research and collaboration between physical and medical scientists. The concept of nano-medicine is one of the most important and exciting ideas ever generated by the...

Developing effective structure-activity/property/toxicity relationships (QSAR/QSPR/QSTR) is very helpful in predicting biological activity, property, and toxicity of a given set of molecules. Regular change in these properties with the structural alteration is the main reason to obtain QSAR/QSPR/QSTR...

The level of malondialdehyde (MDA) in wet tissue of different organs is utilized as a measure of toxic effect. The numerical data on the concentration of MDA in wet tissue of liver, kidneys, brain, and heart of rat is examined as the endpoint which are impacted by different dose (mg/kg), exposure time...