Applications of Gold Nanoparticles in Cancer

Applications of Gold Nanoparticles in Cancer

Solaimuthu Balakrishnan, Firdous Ahmad Bhat, Arunakaran Jagadeesan
ISBN13: 9781522506102|ISBN10: 1522506101|EISBN13: 9781522506119
DOI: 10.4018/978-1-5225-0610-2.ch008
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MLA

Balakrishnan, Solaimuthu, et al. "Applications of Gold Nanoparticles in Cancer." Integrating Biologically-Inspired Nanotechnology into Medical Practice, edited by B.K. Nayak, et al., IGI Global, 2017, pp. 194-229. https://doi.org/10.4018/978-1-5225-0610-2.ch008

APA

Balakrishnan, S., Bhat, F. A., & Jagadeesan, A. (2017). Applications of Gold Nanoparticles in Cancer. In B. Nayak, A. Nanda, & M. Bhat (Eds.), Integrating Biologically-Inspired Nanotechnology into Medical Practice (pp. 194-229). IGI Global. https://doi.org/10.4018/978-1-5225-0610-2.ch008

Chicago

Balakrishnan, Solaimuthu, Firdous Ahmad Bhat, and Arunakaran Jagadeesan. "Applications of Gold Nanoparticles in Cancer." In Integrating Biologically-Inspired Nanotechnology into Medical Practice, edited by B.K. Nayak, Anima Nanda, and M. Amin Bhat, 194-229. Hershey, PA: IGI Global, 2017. https://doi.org/10.4018/978-1-5225-0610-2.ch008

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Abstract

This chapter deals with the applications of gold nanoparticle in cancer and various strategies to target cancer cells by using gold nanoparticles. They are in great demand for biomedical applications such as DNA/Protein detection, bimolecular regulators, cell imaging and cancer cell diagnostics. The ability to tune the surface of the particle provides access to cell –specific targeting and controlled drug release. Depending on their size, shape, degree of aggregation, and local environment, gold nanoparticles can appear red, blue, or other colors. The novel drug delivery systems offer the opportunity to improve poor solubility, limited stability, bio distribution, and pharmacokinetics of drug as well as offering the potential ability to target specific tissues and cell types. The multifunctional gold nanoparticles are attractive organic –inorganic hybrid material composed of an inorganic metallic gold core surrounded by an organic or bimolecular monolayer they provide desirable attributes for the creation of drug delivery in cancer.

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