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Top1. Introduction
Present scenario the foremost challenge is controlling the evolution of diabetes. It is not possible to easily identify the side effects caused by diabetic immediately (Nishant,karthik, 2015). Diabetes is a lifelong disease which is caused by the reduced insulin production or by decreased potential to use insulin. Early diagnosis is very important in preventing health complication in diabetic patients. Without the proper treatment diabetes can lead to very high blood sugar level which can result in long term damage to various tissues and organs like heart, kidney and eyes, etc. (Shobha & Rajeshwari, 2014).
Processing and analysis of images and computer vision techniques are used generally today in every fields of medical science and specially to modernized ophthalmology, as it is heavily dependent on retinal visual alignment signs (Ashok & Sankari, 2017; Padmalal & Kennedy, 2014). Retina is a forth extension of brain and its blood vessels. Image of the retina deal about ophthalmic, retinal and systemic diseases. Although the retinal fundus photographs are accessible and suitable for screening these diseases, a huge number of observations will increase burden for ophthalmologists. Computerised analysis of fundus images of retina can potentially reduce workload of ophthalmologists and even improve efficiency of diagnosis (Narohna & Prabakar, 2013).
1.1. Diabetic Maculopathy
Macula is a significant area responsible for sharp colour vision, it is located at central part of the retina in between inferior and superior temporal vascular arcades (Punnolil, 2013). Detection of macula is an essential module for building a computerised system to grade the DM. It is macular area of the eye which effects DM upsetting the whole central vision of eye and in severe cases it leads to total vision loss (Tariq, Akram, Shaukat et al., 2012). Maculopathy is caused when exudates occurs around the macular area. Exudates are caused by the flowing of blood from blood vessels (BV) which results in yellowish deposition of protein around the retina. The centre of macula is termed as fovea which is greatly responsible for very minute specifications in an image. DM occurs when exudates present near or on the macula effecting central eyesight (Rahim, Palade, Jayne et al., 2015). Maculopathy is classified into three different levels depending on abnormalities position present from the centre part of the macula. If the abnormality is present far away from neighbourhood of macula, then it is mild stage. If abnormalities are present at the neighbourhood of the macula it is moderate stage. Abnormalities will be present over macula in severe stage (Medi & Dandapat, 2014). Computerized methods of DM screening helps to save cost, time and eyesight of patients compared to the manual screening methods of diagnosis.
Top2. Literature Survey
Grading of maculopathy is a challenging task for both computerised systems and medical doctors. A plenty of researches have been carried out to lower the time consumption and observer fatigue during digital screening of the images in order to identify maculopathy. Early detection of the diabetic maculopathy disease is possible by automated image analysis techniques which can be regarded as a manifestation of the diabetes on retina. A brief review of some recent researches is presented here.