This chapter introduces the concept of Supply Chain Management (SCM). It provides a broad definition of supply chain, the drivers for integrated supply chains design, and current challenges in global supply chains. More importantly, this chapter provides the reader an insight into aligning corporate strategy, people mindset, process design, and technology in designing an integrated supply chain. A real-life example in the health care industry is provided. The example aims to give readers the identification of supply chain bottlenecks, the right methodology to map the AS IS processes, and the redesign of simplified supply chain processes. Finally, the guidelines for supply chain management implementation issues, such as vendor selections and team building, are addressed.