Tomorrow’s business environment will make it increasingly difficult for businesses to operate efficiently. To gain the needed edge, in the global economy, many businesses are looking towards information technology. By utilizing technology as a conduit, companies are able to leverage their greatest asset: their internal knowledge base. This chapter presents a framework for architecting enterprise-wide object based information systems. These next-generation systems maximize information value throughout the enterprise, while reducing development time and effort throughout the system lifetime. By presenting a complex concept in a pragmatic fashion this chapter should provide benefit for both information architects and business managers.