This article develops an environment for mobile e-learning that includes an interactive course, virtual online labs, an interactive online test, and lab-exercise training platform on the fourth generation mobile communication system. The Next Generation Learning Environment (NeGL) promotes the term “knowledge economy.” Internetworking has become one of the most popular technologies in mobile e-learning for the next generation communication environment. This system uses a variety of computer embedded devices to ubiquitously access multimedia information, such as smart phones and PDAs. The most important feature is greater available bandwidth. The learning mode in the future will be an international, immediate, virtual, and interactive classroom that enables learners to learn and interact.