This chapter provides an introduction, review and study of mobile businesses with emphasis on its supporting mobile technologies and wireless networking. The chapter first discusses the concept of mobile business where opportunities, motivations and needs for this type of business are studied. Following this discussion, the chapter studies the current status of mobiles business, key hardware and software solutions (business applications) available on the market. The chapter also discusses different mobile devices, communication infrastructure, supporting networks and other crucial components that make businesses mobile and able to be conducted anytime and anywhere. Finally, an extended discussion is focused on issues and future developments of mobile businesses along with some recommendations, and suggestions regarding mobile business.