The retention of women in Information Technology (IT) is a global problem. This chapter reflects on the results of a comprehensive study of women in the South African IT Industry. Areas covered are demographics, experience and qualifications, the work environment, discrimination, gender issues, technical abilities, mentors and other issues related to women in the IT industry. Factors affecting the retention of women in the South African IT Industry are identified, and popular beliefs with regard to the preferences of female IT employees are examined. The authors believe that the findings reported on in this chapter can provide valuable insights that can be used by companies world-wide to enhance employment policies as well as recruitment and retention strategies aimed at women in IT.