Significant changes in information technology (IT), the Internet, and e-business technology have increased the need for continuous and agile data access, in particular for mission-critical applications. Modern business computing has evolved into an organizational engine that drives business and provides a powerful source for competitive advantage. IT has been integrated into organizational operations and activities in a way that application downtime is not an option since each hour, even minute of downtime may generate negative financial effects. In order to achieve higher levels of competitiveness, business has to be continuous from data availability perspective and agile with regard to data access. An enterprise information system (EIS) can be qualified as “high-quality” in terms of its architecture, application platform, and information it can provide to users but if that information is unavailable when it is needed by customer, manager, or any other end user, the value of that EIS simply becomes “zeroed” from end-users’ point of view. The chapter presents a framework for implementation of continuous computing technologies for improving business continuity. The framework is presented within a systemic view of developing an “always-on” enterprise information system.