Computers and the Internet are now pervasive and essential parts of our lives: we use them at work and at home to gather information, for entertainment, and, increasingly, to do business. The Internet allows people to chat with others from all over the world, to follow the news from every continent, and conveniently to shop online at home or at the office. This book chapter covers two important and related concepts: Web design and e-commerce. The section on Web design starts with the overall picture of the Internet, history, Web authoring tools, design rules as well as introducing some research findings on Web design. E-commerce is introduced with definitions, technological acceptance model, online payment methods, online marketing and future developments.